Pitman s primary research interests are in fine needle aspiration biopsy of the liver and pancreas. Wassim kassouf completed a fellowship in urologic oncology at the university of texas md anderson cancer center in houston. The lung was a possible or probable origin in another two cases that table 2. Richard demay, md university of chicago, chicago, usa martha pitman, md harvard medical school, boston, usa vinod b. Her primary research interests center on the role of cytology in the preoperative diagnosis and management of patients with pancreatic cysts. Highgrade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than positive cytology. October 2016 in lecture theatre3 at 5pm at royal free hospital dr. The papanicolaou society of cytopathology system for reporting. This demands that pathologists and cytotechnologists practicing in the usa undertake yearly testing using. We analyzed the utility and relative costeffectiveness of fineneedle aspiration biopsy fnab in the clinical investigation of.
Fna, terminology and nomenclature of pancreatobiliary disease, ancillary testing, and postbiopsy treatment and management. Definitions, criteria and explanatory notes pitman, martha bishop, layfield, lester james on. Shidham, md, fiac, frcpath wsu school of medicine, detroit, usa executive editor. The value of cytology in preoperative diagnosis vicente moralesoyarvide md, won jae yoon, md2, thun ingkakul md, david g forcione md, brenna casey, md, william r brugge md, carlos fernandezdel castillo md, and martha b pitman md cancer cytopathology. Grade atypical epithelial cells in pancreatic mucinous cysts are a more accurate predictor of malignancy than positive cytology. Free cytology books download ebooks online textbooks. Journal of the american society of cytopathology editorial. Publication date 1921 topics natural sciences, biological sciences in general, general genetics.
Nicusor iftimia, sevdenur cizginer, vikram deshpande, martha pitman, servet tatli, nicolaeadrian iftimia, daniel x hammer, mircea mujat, teoman ustun, r. Guidelines for pancreaticobiliary cytology from the. Hga is most accurately identified in mucinous cyst fluids by. Cytology sample collection and preparation for veterinary. Pitman, md massachusetts general hospital massachusetts general hospital phone. Pitman, md clinicians corner the value of urine cytology in the workup of hematuria wassim kassouf, md, cm, frcsc, associate professor, department of urology, mcgill university health center dr. Your story matters citation yoon, won jae, and martha bishop pitman. Pitman has written and lectured extensively on the clinical utility of fine needle aspiration biopsy, particularly of the liver and pancreas. Cytopathology laboratory massachusetts general hospital. Proper triage and processing of the cytologic specimen is pivotal in making a diagnosis due to the need for ancillary testing in addition to cytological evaluation, which is especially true in the diagnosis of pancreatic cysts. Pdf on jun 12, 2014, lester james layfield and others published pancreaticobiliary tract cytology. The main purpose of urine cytology is to detect highgrade urothelial carcinoma. A followup study with corresponding histology and significance of predicting dysplasia by human papillomavirus dna testing.
Cytologic characteristics of circulating epithelioid cells. Definitions, criteria, ancillary testing and management will provide the reader with a unified approach to diagnosing and reporting interpretations of cytologic specimens obtained from the pancreaticobiliary tract. Richard demay, university of chicago, chicago, usamd martha pitman, md harvard medical school, boston, usa vinod b. Her focus of research is on current methods of preoperative diagnosis of pancreatic cysts, particularly mucinous cysts of the pancreas. Recent updates on the role of micrornas in prostate cancer, oudai hassan, aamir ahmad, seema sethi, and fazlul h. Shidham, md, fiac, frcpath wsu school of medicine, detroit, usa. Pitman is the director of the cytopathology laboratory at massachusetts general. This may involve use of immunohistochemistry, flow cytometry. Clinical evaluation, imaging studies, indications for. Layfield, md2 the newest installment on stateoftheart standards of practice in cytopathology from the papanicolaou society of cytopathology psc focuses on the pancreaticobiliary system. Venue and lectures aula marull, imim hospital del mar.
Ali, muriel genevay, ed stelow, md,mari mino kenudson. Is the study of cells structures and their functions. Journal of the american society of cytopathology vol 7. Evaluation of pancreatic lesions that may be interpreted. Martha pitman, md, of massachusetts general hospital, and lester layfield, md, of the university of missouri, spearheaded a nearly threeyear effort to generate guidelines for cytologic diagnosis and recommendations under the auspices of the papanicolaou society of cytopathology, a united states and canadian academy of pathology companion society. Diagnostic terminology and criteria for the cytologic diagnosis of thyroid lesions tarik m. Shidham, md, fiac, frcpath med college of wi, milwaukee, usa executive editor. Cytology samples can be easily obtained preoperatively, often without general anaesthesia and sometimes even without sedation, and can be used to screen patients for more comprehensive diagnosis. Department of pathology school of medicine wayne state. Use features like bookmarks, note taking and highlighting while reading the bethesda system for reporting cervical cytology.
Dr martha bishop pitman british association for cytopathology. The papanicolaou society of cytopathology has developed a set of guidelines for pancreatobiliary cytology including indications for endoscopic ultrasound eus guided fineneedle aspiration fna biopsy, techniques of eusfna, terminology and nomenclature of pancreatobiliary disease, ancillary testing and postbiopsy treatment and management. Hospital mgh and a professor of pathology at harvard. Pitmans phone number, address, hospital affiliations and more. I do want to brag that this effort was spearheaded by two psc past presidents drs. Cancer cytopath 2010 high grade atypical glandular epithelium high. Fine needle aspiration cytology is less costly than surgical biopsy in both sample collection and laboratory analysis. Pdf the papanicolaou society of cytopathology system for. Pitmans primary research interests are in fine needle aspiration biopsy of the liver and pancreas. The presence of a pathology report is to convey clinically useful diagnostic information relevant to the findings on the slide that can be used for treatment and management of the patient. Manual for cytology pdf 44p this book covers the following topics. Faquin, md phd martha pitman, md fernando schmitt, md, phd, fiac. Citescore values are based on citation counts in a given year e. Pitman is the director of the cytopathology laboratory at massachusetts general hospital mgh and a professor of pathology at harvard medical school hms.
In certain countries such as the usa, the federal government has mandated a national proficiency testing program for gynecologic cytology. We want to help promote all of your pathology related books. Standardized terminology and nomenclature for pancreatobiliary cytology. This text and the terminology developed by the papanicolaou society of cytopathology p. One of the most important concept in biology is that a cell is a basic structural and functional unit of living organism.
Brugge, differentiation of pancreatic cysts with optical coherence tomography oct imaging. The papanicolaou society of cytopathology guidelines. Definitions, criteria, and explanatory notes kindle edition by nayar, ritu, wilbur, david c download it once and read it on your kindle device, pc, phones or tablets. Latest guidelines for pancreatobiliary cytologya recap. Pathologist, massachusetts general hospital subspecialty head and director, cytopathology laboratory professor of pathology, harvard medical school. The papanicolaou society of cytopathology recommendations for pancreatic and biliary cytology. Cytopathologic touch preparations imprints from core needle biopsies. All 100% were p16 negative on cell block sections of cervical cytology specimen. The papanicolaou society of cytopathology consensus. Hpv testing performed in last 6 months in 7 cases was positive in 3 43% cases. Role of diagnostic cytology, collection and preparation of material for cytodiagnosis, cytopreparatory techniques of serous effusions, fixation of cytology specimens, staining methods in cytology. Diagnosing malignancy in bile duct brushings is highly challenging. Jun 02, 2014 pitman mb, genevay m, yaeger k, chebib i, turner bg, minokenudson m, et al.
An additional case was diagnosed at autopsy one month after the investigation of the breast lesion. Cytology specimen management, triage and standardized. Brugge, md, and mari minokenudson, md cancer cytopathology 2014. Mary rego, heather smith, brenda sweeney, martha pitman, david wilbur. The clinical application and cost analysis of fineneedle. Cytologic characteristics of circulating epithelioid cells in. Pdf on jun 12, 2014, lester james layfield and others published pancreaticobiliary. Overview of origins and subtypes of metastatic tumors in the breast origin subtype number of cases with cyt.
Guidelines for pancreaticobiliary cytology from the papanicolaou society of cytopathology. Cytology specimen management, triage and standardized reporting of fine needle aspiration biopsies of the pancreas the harvard community has made this article openly available. Cervical cytology of the diagnosis atypical squamous cells, cannot exclude high grade squamous intraepithelial lesion. The bethesda system for reporting cervical cytology. Abstract the recent advances in pancreas cytology specimen sampling methods have enabled a specific cytologic diagnosis in most cases. Standardized terminology and nomenclature for pancreatobiliary. Martha bishop pitman, md, department of pathology, massachusetts general hospital, 55 fruit street, boston, ma 01907. The recent advances in pancreas cytology specimen sampling methods have enabled a specific. The papanicolaou society of cytopathology has developed a set of guidelines for pancreatobiliary cytology including indications for endoscopic ultrasound eus.
A step toward recommendations and guidelines was arranged in collaboration with american society of cytopathology. Shidham, md, fiac, frcpath medical college of wisconsin. Sepe, bhavani moparty, martha bishop pitman, john r. Jun 30, 2017 diagnosing malignancy in bile duct brushings is highly challenging. Layfield, md2 the newest installment on stateoftheart standards of practice in cytopathology from the papanicolaou society of cyto. The papanicolaou society of cytopathology system for. Is the study of cells structures and their functions a cell is an organized independent mass of protoplasm nucleus and cytoplasm which makes the basic primary structure of an organism. Hahn p, eisenberg pj, pitman mb, gazelle gs, mueller pr. The papanicolaou society of cytopathology system for reporting pancreaticobiliary cytology will provide the reader with a unified approach to diagnosing and reporting cytologic specimens obtained from the pancreaticobiliary tract. With this principle in mind, the paris system tps working group, composed of cytopathologists, surgical pathologists, and urologists, has proposed and published a standardized reporting system that includes specific diagnostic categories and cytomorphologic criteria for the reliable diagnosis of highgrade. Clinical evaluation, imaging studies, indications for cytologic study, and preprocedural requirements for duct brushing studies and pancreatic fna. Cytologic predictors of malignancy in bile duct brushings. Journey toward bethesda style guidelines from the papanicolaou society of cytopathology. Educational curricula for cytomorphology criteria, laboratory methodologies, and quality assurancequality control processes learned over the years from the pap test form a foundation on which the rest of cytopathology expands.
Pitman mb, centeno ba, ali sz, genevay m, stelow e, minokenudson m, fernandezdel castillo c, max schmidt c, brugge w llps of c. A cell is an organized independent mass of protoplasm nucleus and cytoplasm which. Free cytology books download ebooks online textbooks tutorials. Guidelines for pancreaticobiliary cytology from the papanicolaou. Tissue samples are considered the gold standard in diagnosis. The papanicolaou society of cytopathology system for reporting pancreaticobiliary cytology. May 2016in the era of personalized medicine 1 it is paramount to collect samples that will have sufficient material not only for an accurate diagnosis but also in many cases for prognostication or eligibility for targeted therapy or both. Sarcoidosis is a prevalent disease of unknown cause characterized by granulomatous inflammation that often creates deep andor superficial mass lesions. View pdf cite save eusguided fna for the diagnosis of gi stromal cell tumors.
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